Prediction Southampton's better form, attacking threat, and Oxford's vulnerabilities make the visitors strong favorites. Expect a 1-2 or 0-2 away win, with over 2.5 goals likely given trends (Southampton games often high-scoring, Oxford conceding regularly). Implied win probability for Southampton is around 48-54%. Asian Handicap Prediction The common Asian handicap line is Southampton -0.5 (equivalent to Southampton to win outright) at around -120 to -122 odds. Back Southampton -0.5, as their quality edge, Oxford's poor run (especially defensively), and managerial uncertainty provide solid value for an away victory. If the line is -0.75, it offers higher returns with half-win potential on a one-goal margin, but -0.5 remains the safer play aligning with predictions.